ameliorative effects of metformin on renal histologic and biochemical alterations of gentamicin-induced renal toxicity in wistar rats

نویسندگان

hamid nasri department of nephrology, division of nephropathology, isfahan university of medical sciences, isfahan, iran

چکیده

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منابع مشابه

Ameliorative effects of metformin on renal histologic and biochemical alterations of gentamicin-induced renal toxicity in Wistar rats

BACKGROUND The aim of this study was to test the potential properties of metformin (MF) to protect the kidney from gentamicin (GM)-induced renal toxicity. MATERIALS AND METHODS In this preclinical study, 50 male Wistar rats were randomly divided into five groups of 10 rats in each. In the first group (group I), they were kept in the same condition as others without receiving drugs for 10 days...

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Protective Effects of Co-Treatment With Hydroethanolic Extract of Origanum Vulgare on Gentamicin-Induced Renal Toxicity in Rats

Objective: Renal toxicity and ototoxicity are considered as the main side effects of aminoglycoside antibiotics, such as gentamicin. The present study aimed to investigate the effect of co-treatment by origanum vulgare extract on the gentamicin-induced renal toxicity. Methods: Adult male Wistar rats in the weight range of 200 to 250 grams were randomly assigned into four groups (n = 8): contro...

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The Protective Roles of Zinc and Magnesium in Cadmium-Induced Renal Toxicity in Male Wistar Rats

Background: Cadmium (Cd) is a heavy metal that has widespread use. It enters the food chain in different ways, including soil and water. Cadmium can cause dysfunction of different body organs. Zinc (Zn) and magnesium (Mg) supplementation can have protective effects against cadmium toxicity due to their antagonistic and antioxidants properties. This study examines the influence of supplemental...

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the effect of aqueous extract of garlic on formalin-induced pain in male rats

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Renal Effects of Anchomanes difformis Crude Extract in Wistar Rats

Objective:  Anchomanes difformis is a member of the plant family Araceae which is used as a diuretic but also has other medicinal applications. This study investigates the dietary effects of A. difformis on the kidneys of adult wistar rats. Materials and Methods: Sixteen rats were used and were weighed, before and after the experiment. All rats were randomly divided into four groups. All groups...

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عنوان ژورنال:
journal of research in medical sciences

جلد ۱۸، شماره ۷، صفحات ۶۲۷-۰

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